School of Molecular Sciences

Carbohydrate chemistry and chemical glycobiology

Further information

Contact

Glycobiology is the study of the structures and roles of carbohydrates in biology.

Carbohydrates are present in every living system and traditionally, have been known for their role in structural integrity and as energy sources.

Recently, however, carbohydrates have been shown to be involved in a variety of fundamental biological processes such as protein folding and trafficking, as well as cellular signaling and regulation. As a result glycoconjugates continue to be uncovered as important factors in health and disease. Furthermore due to their inherent chirality, carbohydrates are excellent sources of starting materials for advanced synthesis.

The laboratory headed by Dr. Stubbs is engaged in the study of:

  • The development of chemical tools to both perturb and understand the action carbohydrate-processing enzymes which act on glycoconjugates.
  • Use of these chemical tools to gain new understanding as to how these enzymes and glycoconjugates mediate biological processes.
  • The development and use of new synthetic and chemical strategies utilising carbohydrates to address the preparation of molecules of interest.